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  VitiDerm® topical gel

  Non-greasy, paraben-free gel with superoxede dismutase - SOD and catalase, Ginkgo biloba, calcium chloride...Formulated with an optimum combination of ingredients for depigmentation.

  
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  VitiDerm® tablets to stimulate skin pigmentation.

  Formulated with an optimum combination of ingredients VitiDerm^® delivers a concentrated cocktail of active substances like Acerola which protect DNA, vitamine A, vitamin E which prevent cells from oxydative damage, ascorbyl palmitate which enable a normal metabolism, selenium...

  
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  UVB Narrowband Lamp Dermalight 80 for Vitiligo treatment

  "The selective phototherapy (311 nl) has demonstrated efficacy for the treatment of vitiligo and has become the preferred treatment of vitiligo, both in children than in adults.

  The technique has many advantages...

  

VitiDerm^®

Gel and softgels

Vitiligo is characterized by a catalase deficiency that leads to the vacuolization of the melanocytes and keratinocytes.

VitiDerm^® is an innovative product from DermoPro.

Oxidative stress and depigmentation

Due to oxidative stress (high concentrations of free radicals) vacuolization and cell death occur.

These include a gradual loss of melanocytes^(1)(2)(3)(4) and an abnormally high level of hydrogen peroxide (H₂O₂) in the epidermis, leading to oxidative stress and oxidation of proteins and lipids.⁽⁵⁾

Keratinocytes in vitiligo lesions have proinflammatory responses, which can be inhibited through the combination of SOD and Catalase.

Concentration of hydrogen peroxide (H₂O₂) in vitiligo patients

Numerous recent studies have pinpointed certain anomalies in patients with skin depigmentation.

In patients with vitiligo, it has been shown that a deficiency in catalase, vitamins and minerals is one of the causes of oxidative stress.^{(7) (12)}.

Oxidative stress damages the melanocyte membranes, the cells which are essential for skin pigmentation ⁽⁶⁾.

Cell damage in patients with vitiligo

 

Restoring the physiological conditions for pigmentation

• Melon extract : Superoxede dismutase - SOD and catalase

• Ginkgo Biloba : Prevent cells from oxydative stress like melon
  

• Selenium : Contributes to a normal immune system and to protect cells from oxidative stress

• Vitamins C : Contributes to a normal immune system and to protect cells from oxidative stress

• Vitamins A : Metabolism of iron (important to vehicule oxygen), protection of DNA, proteins and lipids from oxidative damage
  maintenance of normal skin, maintenance of the normal function of the immune system

• Vitamin E : Contributes to protect cells from oxidative stress, maintenance of the normal function of the immune system, protection of DNA, proteins and lipids from oxidative damage, maintenance of normal skin, regeneration of the reduced form of vitamin C

• Silica : Enable a normal development of the conective tissue

• Ascorbyl palmitate : : Contribution to normal energy-yielding metabolism

• Acerola : Protect DNA and prevent cells from oxidative stress (80 more powerfull than vitamin C)

• Green tea, calcium carbonate